Thyroid profile is ordered to see the thyroid dysfunctioning when the thyroid gland is not functioning properly resultant increased or decreased amounts of thyroid hormones. When TSH concentration increases it called Hypothyroidism and when it decreases it called Hyperthyroidism. Signs and symptoms may varies in hypo- or hyperthyroidism conditions. Signs and symptoms of hypothyroidism may include: Weight gain, Dry skin, Constipation, Cold intolerance, Puffy skin, Hair loss Fatigue, and Menstrual irregularity in women. Signs and symptoms of hyperthyroidism may include: Increased heart rate, Anxiety, Weight loss, Difficulty sleeping, Tremors in the hands, Weakness, Diarrhea, Puffiness around the eyes, dryness, irritation, or bulging of the eyes. Panel includes - T3, T4, TSH