Monitoring intensity of oral anticoagulant therapy when combined with INR reporting Screening assay to detect deficiencies of 1 or more coagulation factors (factors I, II, V, VII, X) due to: -Hereditary or acquired deficiency states -Vitamin K deficiency -Liver disease -Specific coagulation factor inhibitors Screening assay to detect coagulation inhibition ("circulating anticoagulants") associated with: -Specific coagulation factor inhibitors -Lupus-like anticoagulant inhibitors (antiphospholipid antibodies) -Nonspecific PT inhibitors (eg, monoclonal immunoglobulins, elevated fibrin degradation products)Prothrombin Time is done to assess the extrinsic and common coagulation pathway from Factor VII through fibrin formation. Results are interpreted based on INR. A prolonged INR suggests a potential bleeding disorder.